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Zyban, Bupropion, Smoking Cessation Medication Resources

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Newly Approved Drug Therapies, Drug Name: Zyban Sustained-Release Tablets:"Zyban Sustained-Release Tablets have been approved for use as a smoking cessation treatment. It is the first nicotine-free prescription medicine available. It is also the first smoking cessation treatment available in tablet form. Zyban will be available by prescription approximately July 1997."
http://www.centerwatch.com/drug-information/fda-approvals/drug-details.aspx?DrugID=261

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Zyban.com:"ZYBAN is a Totally Different Way To Help You Quit Smoking. Nicotine-Free ZYBAN is prescription-strength medicine. ZYBAN is the first nicotine-free pill approved to help you quit smoking and is available from your health care professional. The first pill that can help reduce your urge to smoke. Users of ZYBAN also get The ZYBAN Advantage Plan® at no additional cost with a prescription for ZYBAN. This support system provides information to help you during the quitting process. And you can now enroll on-line and receive all your materials on the Internet."
http://us.gsk.com/html/medicines/index.html

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Zyban Sustained-Release Tablets: Drugs Approved by the FDA, Center Watch:"Zyban Sustained-Release Tablets have been approved for use as a smoking cessation treatment. It is the first nicotine-free prescription medicine available. It is also the first smoking cessation treatment available in tablet form. Zyban will be available by prescription approximately July 1997. In addition, the medication includes a patient support program Zyban Advantage Plan--at no additional patient cost. The plan provides additional support and specific smoking cessation techniques."
http://www.centerwatch.com/patient/drugs/DRU261.html

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Zyban for smoking cessation:"Bupropion looks better than nicotine replacement therapy. The placebo response rate is the same, but cessation rates are higher, and the NNT, at 8, is lower than that for most nicotine replacement therapies, at about 12-15 (Bandolier 54 ). Given that the smoking of cigarettes has such major health consequences ( Bandolier 9, 14), clearly there will be benefits for some people. Smokers don't have to be depressed to use bupropion. There are adverse effects, and the review [1] quotes a risk of seizures estimated at 1 in 1000, as well as minor adverse effects like nausea and insomnia, but without numbers."
http://www.medicine.ox.ac.uk/bandolier/band79/b79-3.html

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Zyban - a new treatment for nicotine addiction:"Zyban is a drug marketed by Glaxo-Wellcome and has been used, very successfully, to treat nicotine addiction directly. In this case it is different to the way other anti-smoking agents work, such as nicotine gum and patches, since these simply supply an alternative source of nicotine other than cigarettes. Zyban works at the neurological level, reducing the craving for nicotine in any form. At the moment it is licensed in the US, but not yet in the UK. It is potentially extremely important, as this discovery could open the door to finding similar molecules for treating much more serious addiction problems, such as cocaine and heroin, etc."
http://www.chm.bris.ac.uk/motm/zyban/zyban.htm

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Send comments and mail to Andrew Lopez, RN

Created on Wednesday, May 12, 1999

Last updated by Andrew Lopez, RN on Monday, November 22, 2010


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