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Prescription Drugs, Medications, Medicines
AIDS/HIV, Antiviral Antiretroviral Agents,
Didanosine, DDI, Videx

This drug is also known as: Didanosine, DDI, VIDEX chew tabs, VIDEX EC

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didanosine (ddI, Videx, Videx EC), A Simple FactSheet from the AIDS Treatment Data Network:"didanosine, trade name Videx (also known as ddI), is an anti-HIV treatment in a class of drugs called nucleoside analogs. The body breaks down these drugs into chemicals that stop HIV from infecting uninfected cells in the body, but they do not help cells that have already been infected with the virus. As people with HIV lose CD4 cells - one of the immune system's main defenses - they become more likely to get infections and illnesses."


Didanosine (DDI, VIDEX chew tabs, VIDEX EC), About Didanosine, Calgary Health Region:"Didanosine is an antiretroviral drug called a nucleoside reverse transcriptase inhibitor. Didanosine mimics a nucleoside base, which blocks further construction of the virus. When combined with other antiretroviral agents, didanosine can achieve a significant decrease in viral multiplication."


Videx (didanosine), General Information, Center Watch:"A smaller dosage of Videx has been approved for the treatment of HIV infection in adults and children when antiretroviral therapy is warranted. The new Videx tablet is 35% smaller than the original tablet. In addition, the taste has been improved with a mandarin orange flavor. The new Videx tablets will be manufactured in 25 mg, 50 mg, 100 mg, and 150 mg tablets. The new tablet will be available immediately."


Didanosine, What is didanosine, Cincinnati Children's Hospital Medical Center:"Didanosine (Videx®) is a medicine used to treat patients who are infected with the human immunodeficiency virus (HIV). HIV is the virus that causes acquired immune deficiency syndrome (AIDS). This medicine does not cure the virus; it slows down the destruction of the immune system and may help to slow down the progress of the HIV disease."


Didanosine, What key warnings should I know about before taking this medicine, Health and Age:"This medicine may cause severe irritation to the pancreas, damage the liver, or change acid levels in the blood. Closely review the section in this leaflet which tells you when to immediately call your healthcare provider. Pregnant women may be at a high risk of developing a change in acid levels called lactic acidosis when taking stavudine and didanosine together. This combination has rarely caused death. The combination should only be used in pregnant women when the benefit outweighs the risk."


Videx, Why is this drug prescribed, Health Square:"Videx is one of the drugs used to fight the human immunodeficiency virus (HIV)--the deadly cause of AIDS. Over a period of years, HIV slowly destroys the immune system, leaving the body defenseless against infection. Videx disrupts reproduction of HIV, thereby staving off the immune system's collapse."


Didanosine (Systemic), Description, MEDLINEplus:"Didanosine (di-DAN-oe-seen) (also known as ddI) is used in the treatment of the infection caused by the human immunodeficiency virus (HIV). HIV is the virus responsible for acquired immune deficiency syndrome (AIDS).

Didanosine (ddI) will not cure or prevent HIV infection or AIDS; however, it helps keep HIV from reproducing and appears to slow down the destruction of the immune system. This may help delay the development of problems usually related to AIDS or HIV disease. Didanosine will not keep you from spreading HIV to other people. People who receive this medicine may continue to have the problems usually related to AIDS or HIV disease."


Didanosine (ddI, dideoxyinosine), Uses, Nurses PDR:"Advanced HIV infection in adult and pediatric (over 6 months of age) clients who are intolerant of AZT therapy or who have demonstrated decreased effectiveness of AZT therapy. Use in adults with HIV infection who have received prolonged AZT therapy. Treatment of HIV infection when antiretroviral therapy is indicated. AZT should be considered as initial therapy for the treatment of advanced HIV infection, unless contraindicated, since this drug prolongs survival and decreases the incidence of opportunistic infections. May be used as monotherapy for the treatment of AIDS. As first-line component for HIV-1 infections with stavudine plus a protease inhibitor or the nonnucleoside efavirenz."


Didanosine, Indications and Dosage, RXlist:"Dosage All VIDEX formulations should be administered on an empty stomach, at least 30 minutes before or 2 hours after eating. For either a once-daily or twice-daily regimen, patients must take at least two of the appropriate strength tablets at each dose to provide adequate buffering and prevent gastric acid degradation of didanosine. Because of the need for adequate buffering, the 200 mg strength tablet should only be used as a component of the 400 mg once-daily regimen. To reduce the risk of gastrointestinal side effects, patients should take no more than four tablets at each dose. "





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Last updated by Andrew Lopez, RN on Monday, November 22, 2010

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