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This page was prepared by E. Stankowski RN
http://www.nursewing.com
Brand Name: Marplan
Generic Name: Isocarboxazid
Drug Class: Antidepressant, MONOAMINE OXIDASE
(MAO) INHIBITOR
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Marplan, What is this drug for? Centerwatch.com:"Marplan is indicated for the treatment of depression. Because of its potentially serious side effects, it is not recommended as an anti-depressant of first choice in the treatment of newly diagnosed depressed patients.The effectiveness of Marplan for long-term use, meaning longer than 6 weeks, has not been fully evaluated by trials."Thomson CenterWatch
22 Thomson Place, 47F1
Boston, MA 02210-1212
Phone: (617) 856-5900 or Fax: (617) 856-5901
E-mail: visitor@centerwatch.com or cw.mailroom@centerwatch.com
http://www.centerwatch.com/patient/drugs/dru470.html
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Marplan, Pregnancy Precautions, Drugs.com:"A limited study in pregnant women showed an increased risk of birth defects when these medicines were taken during the first 3 months of pregnancy. In animal studies, MAO inhibitors caused a slowing of growth and increased excitability in the newborn when very large doses were given to the mother during pregnancy."Hampstead Trust
ATTN: DRUGS.COM
c/o Network Solutions
P.O. Box 447
Herndon, VA 20172-0447
Phone: (570) 708-8780
E-mail: contact @ drugs.com
http://www.drugs.com/cons/marplan.html
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Marplan, How should I take this medicine? Drugdigest.org:"Take isocarboxazid tablets by mouth. Follow the directions on the prescription label. Swallow the tablets with a drink of water. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking the tablets except on your prescriber's advice."DrugDigest
Expresscripts.com
521 Alton Rd #208,
Miami Beach, FL 33140, US
E-mail: questions@express-scripts.com
http://www.drugdigest.org/DD/DVH/Uses/0,3915,551211|Marplan,00.html#howToTake
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Marplan, Before Using this medicine, Drugstore.com:"USE OF THIS MEDICINE IS NOT RECOMMENDED if you have a history of heart, liver, or kidney conditions; high blood pressure; stroke; or pheochromocytoma."Drugstore.com
407 Heron Drive
Swedesboro, NJ 08085-9810
Phone: (1-800) 378-4786
E-mail: aboutrx@drugstore.com
http://www.drugstore.com/pharmacy/prices/drugprice.asp?ndc=64803003201&trx=1Z5006
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Marplan, Drugs and Foods to Avoid, Healthtouch.com:"Make sure your doctor knows about all other medicines you are using. MAO inhibitors can be very dangerous if used with certain other medicines. You may need to wait at least 14 days between using an MAO inhibitor and using another medicine. Wait 5 weeks if you are changing from Prozac® to Marplan®."Health Touch.com
Cardinal Health, Inc.
7000 Cardinal Place
Dublin, Ohio 43017 US
Phone: (614) 757-5014 or Fax: (614) 757-6014
http://www.healthtouch.com/bin/EContent_HT/dnoteShowLfts.asp?fname=01049&title=Marplan+%28Oral%29%2C+See+%7CISOCARBOXAZID+%28Oral%29+%28Tablet%29+%7C+&cid=HTDRUG
****************************************************
Antidepressant, MONOAMINE OXIDASE (MAO) INHIBITOR, Breastfeeding Precautions, Mayoclinic.com:"Tranylcypromine passes into the breast milk; it is not known whether isocarboxazid or phenelzine passes into breast milk. Problems in nursing babies have not been reported."Mayo Foundation for Medical Education and Research
200 1st St. S.W.
Rochester, MN 55905
E-mail: comments@mayoclinic.com
http://www.mayoclinic.com/invoke.cfm?objectid=49696F78-8835-47FF-B5922D690D9712B5#Before%20Using%20This%20Medicine
****************************************************
Isocarboxazid, Important Warning, Medlineplus:"Studies have shown that children and teenagers who take antidepressants ('mood elevators') such as isocarboxazid may be more likely to think about harming or killing themselves or to plan or try to do so than children who do not take antidepressants. Children younger than 16 years of age should not normally take isocarboxazid.If your child's doctor has prescribed isocarboxazid for your child, you should watch his or her behavior very carefully, especially at the beginning of treatment and any time his or her dose is increased or decreased."National Library of Medicine
8600 Rockville Pike
Bethesda, Maryland 20894
Phone: (301) 496-6308 Fax: (301) 496-4450
E-mail: custserv@nlm.nih.gov
http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a605036.html
****************************************************
Marplan, Storage Guidelines, Pharmacyhealth.net:"Store at room temperature away from moisture and sunlight. Do not store in the bathroom. Your condition can cause complications in a medical emergency."Yourlabtest.com
210 Fairfax Blvd.
Atlanta, GA 30319
Phone: (800) 209-1689.
E-mail: info@medpharmacy.com or info@pharmacyhealth.net
http://www.pharmacyhealth.net/d/marplan-6644.htm
****************************************************
Marplan, Symptoms of OVERDOSE, Rxlist.com:"The lethal dose of Marplan in humans is not known. There has been one report of a fatality in a patient who ingested 400 mg of Marplan together with an unspecified amount of another drug. Symptoms: Major overdosage may be evidenced by tachycardia, hypotension, coma, convulsions, respiratory depression, sluggish reflexes, pyrexia, and diaphoresis; these signs may persist for 8 to 14 days."WebMD
Attn: Office of Privacy
1175 Peachtree Street, NE
Suite 2400
Atlanta, GA 30361
Or call: 866-788-3097
http://www.rxlist.com/cgi/generic/isocarbo_od.htm
****************************************************
Marplan, Precautions when using this medicine, Webmd.com:"Consult your doctor about the need to watch your intake of foods containing tyramine. It is possible consuming tyramine- containing foods while using this medication could cause headache and/or increased blood pressure and could lead to a medical emergency. Tyramine food precautions should be observed for at least 2 weeks after you stop using this medication."WebMD
669 River Drive, Center 2
Elmwood Park, NJ 07407
Phone: (201) 703-3400 or Fax: (201) 703-3401
Sales Support: (1-877) GO-WEBMD
E-mail Contact Form: http://www.webmd.com/about-webmd-policies/about-contact-us
http://my.webmd.com/drugs/drug-11985-Marplan+Oral.aspx?drugid=11985&drugname=Marplan+Oral#precautions
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http://www.prescriptionforviagra.com/drugs/antidepressants.monoamine.oxidase.inhibitors.maoi.marplan.isocarboxazid.htm
Last updated by Andrew Lopez, RN on Monday, January 31, 2011