Aminocaproic Acid oral, When should I be careful taking it, Drug Digest:"This medication should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Consult your doctor before using any medication while breast-feeding. Tell your doctor if you have any pre-existing heart, liver or kidney disease, bleeding disorders or allergies."
http://www.drugdigest.org/DD/DVH/Precautions/0,3916,6018|Aminocaproic%2BAcid%2Boral,00.html

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Amicar, Common uses, Drugstore.com:"This medicine is an antihemorrhagic used to treat certain bleeding problems associated with surgery, blood disorders, and liver disease. It may also be used to treat other conditions as determined by your doctor."
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Aminocaproic Acid, When This Medicine Should Not Be Used, healthtouch.com:"You should not use this medicine if you have had an allergic reaction to aminocaproic acid. In some cases, you should not use this medicine if you have a blood clotting problem called disseminated intravascular coagulation (DIC)."
http://www.healthtouch.com/bin/EContent_HT/dnoteShowLfts.asp?fname=04939&title=AMINOCAPROIC+ACID+(Injection)+(Injectable)+&cid=HTDRUG

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Antifibrinolytic Agents (Systemic), Missed dose, Mayoclinic.com:"For aminocaproic acid (e.g., Amicar): If you miss a dose, take it as soon as possible. However, if you do not remember until it is almost time for your next dose, double the next dose. Then go back to your regular dosing schedule."
http://www.mayoclinic.com/health/drug-information/DR202058

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Aminocaproic Acid Injection, SIDE EFFECTS, Medicinenet.com:"Nausea, headache, diarrhea, or fatigue may occur. If any of these effects persist or worsen, notify your doctor. Unlikely but report promptly: irregular or unusually slow pulse, pain/redness at the injection site. Very unlikely but report promptly: vision changes, one-sided weakness, ringing in ears or loss of hearing, chest pain, mental/mood changes, muscle pain or weakness, change in amount of urine, seizures, prolonged menstruation, ejaculation problems. In the unlikely event you have an allergic reaction to this medication, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist."
http://www.medicinenet.com/aminocaproic_acid-injection/article.htm

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Aminocaproic Acid--Oral, Side Effects, PersonalMd.com:"Though usually well tolerated this drug may cause stomach upset, nausea, loss of appetite, diarrhea, headache, dizziness or nasal stuffiness. If these symptoms continue or become bothersome, inform your doctor. Notify your doctor if you experience weakness, muscle aches, ringing in the ears, skin rash, mental confusion, seizures, persistent sore throat or unusual bleeding or bruising. In the unlikely event you have an allergic reaction to this drug, seek medical attention immediately. Symptoms of an allergic reaction may include difficulty breathing, fever, itching or swelling. If you notice other effects not listed above, contact your doctor or pharmacist."
http://www.personalmd.com/drgdb/199.htm

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Aminocaproic Acid, Indications, RXlist:"AMICAR is useful in enhancing hemostasis when fibrinolysis contributes to bleeding. In life-threatening situations, fresh whole blood transfusions, fibrinogen infusions, and other emergency measures may be required.

Fibrinolytic bleeding may frequently be associated with surgical complications following heart surgery (with or without cardiac bypass procedures) and portacaval shunt; hematological disorders such as aplastic anemia; abruptio placentae; hepatic cirrhosis; neoplastic disease such as carcinoma of the prostate, lung, stomach, and cervix."
http://www.rxlist.com/cgi/generic/amicarpre_ids.htm

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AMICAR®, Action And Clinical Pharmacology, RxMed.com:"Epsilon aminocaproic acid is a monoaminocarboxylic acid which acts as an effective inhibitor of fibrinolysis. The beneficial fibrinolysis-inhibitory effects of aminocaproic acid appear to be principally via inhibition of plasminogen activator substances and to a lesser degree, through antiplasmin activity. The drug is absorbed rapidly following oral administration. Whether administered by the oral or i.v. route, a major portion of the compound is recovered unmetabolized in the urine. The renal clearance of aminocaproic acid is high (about 75 % of the creatinine clearance). Thus, the drug is excreted rapidly. After prolonged administration, aminocaproic acid distributes throughout both the extravascular and intravascular compartments of the body and readily penetrates human red blood and other tissue cells. tag_IndicationsIndications."
http://www.rxmed.com/b.main/b2.pharmaceutical/b2.1.monographs/CPS-%20Monographs/CPS-%20(General%20Monographs-%20A)/AMICAR.html

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Amicar, Adverse Reactions, RXMed.com:"Occasionally nausea, cramps, diarrhea, dizziness, tinnitus, malaise, conjunctival suffusion, nasal stuffiness, headache, myopathy and skin rash have been reported as results of the administration of aminocaproic acid. Only rarely has it been necessary to discontinue or reduce medication because of one or more of these effects. There have also been some reports of dry ejaculation during the period of aminocaproic acid treatment. These have been reported to date only in hemophiliac patients who received the drug after undergoing dental surgical procedures. However, this symptom resolved in all patients within 24 to 48 hours of completion of therapy."
http://www.rxmed.com/b.main/b2.pharmaceutical/b2.1.monographs/CPS-%20Monographs/CPS-%20(General%20Monographs-%20A)/AMICAR.html

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Aminocaproic Acid IV, Precautions, WebMD.com:"Tell your doctor your medical history, including: any allergies, blood clotting disorders (e.g., hemophilia), kidney disease, bleeding within the brain, bleeding of the urinary system. A preservative (benzyl alcohol) which may be found in this product or in the liquid used to mix this product (diluent) can infrequently cause serious problems (sometimes death), if given in large amounts (more than 100 mg/kg daily) to an infant during the first months of life (neonatal period). The risk is also greater with low birth weight infants. Symptoms include sudden gasping, low blood pressure, or a very slow heartbeat. Report these symptoms to the doctor immediately should they occur. If possible, a preservative-free product should be used when treating neonates."
http://www.webmd.com/drugs/drug-12048-Aminocaproic+Acid+Intravenous.aspx?drugid=12048&drugname=Aminocaproic+Acid+Intravenous

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Aminocaproic Acid, Range and Frequency, Whole HealthMd:"Adults: Initial dose is 5 g, then 1 or 1.25 g per hour, three or four times a day after the initial dose. The maximum daily dose is 30 g per day. It may be taken by mouth or intravenously. Children: Initial dose is 45.5 mg per lb of body weight, followed by 15.1 mg per lb, three or four times a day, for two to eight days."
http://www.wholehealthmd.com/refshelf/drugs_view/1,1524,19,00.html

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