Tolterodine Tartrate(Detrol LA), Precautions, DetrolLA.com:"DETROL LA should be used with caution by patients with any of the following conditions: significant bladder outflow blockage (slow urinary stream), because of the risk of urinary retention; gastrointestinal blockage disorders, such as pyloric stenosis (a narrowing of the opening where the stomach empties into the small intestine), because of the risk of gastric retention; narrow-angle glaucoma that is being treated; and liver or kidney disease. For patients with liver disease or kidney disease the recommended dose is 2 mg daily. Medicines like DETROL LA may cause blurred vision, dizziness, or drowsiness."
http://www.detrolla.com/information.asp

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Tolterodine, Indications, RXlist:"DETROL Tablets are indicated for the treatment of patients with an overactive bladder with symptoms of urinary frequency, urgency, or urge incontinence."
http://www.rxlist.com/cgi/generic2/tolter_ids.htm

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Tolterodine, Proper Use, MEDLINEplus:"Take this medicine only as directed. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects. The extended release capsules should be taken with liquids and swallowed whole."
Office of Communications and Public Liaison National Library of Medicine
8600 Rockville Pike Bethesda, Maryland 20894
Phone: (301) 496-6308 Fax: (301) 496-4450 email: publicinfo@nlm.nih.gov
http://www.nlm.nih.gov/medlineplus/druginfo/tolterodinesystemic203475.html

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Tolterodine Tartrate(Detrol), Clinical Results, CenterWatch.com:"Three placebo-controlled, 12 week studies were held involving a total of 339 patients who received Detrol 2 mg twice daily and 177 patients who received the placebo. The majority of patients were Caucasian (95%) and female (75%), with the mean age being 60 years of age (range 19-91). At their entrance into the study almost all patients perceived symptoms of urgency (98%) and increased frequency of micturitions (89%) and urge incontinence (83%). These characteristics were balanced across treatment groups for all three studies."
http://www.centerwatch.com/patient/drugs/dru658.html

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Tolterodine(Detrol), Bladder and bowel dysfunction, RemedyFind.com:"Detrol (Tolterodine) is a medication used to control urinary incontinence. It relaxes the muscle cells of the urinary tract and increases urinary bladder capacity. By decreasing muscle spasms of the bladder, Tolterodine reduces the need for frequent urination caused by the spasms."
http://remedyfind.com/rm-1146-Detrol.asp

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Tolterodine Tartrate, Side Effects, xreferences:"Side effects: include dry mouth, constipation, indigestion, nausea, abdominal discomfort, flatulence, vomiting, headache, dry skin, dry eyes, drowsiness, nervousness, tingling in the fingers, and (more rarely) blurred vision, chest pain, and difficulty in passing urine."
http://www.xrefer.com/entry/475791

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Tolterodine, Clinical Pharmacology, Mosby's DRUG Consult:"Tolterodine is a competitive muscarinic receptor antagonist. Both urinary bladder contraction and salivation are mediated via cholinergic muscarinic receptors. In the anesthetized cat, tolterodine shows a selectivity for the urinary bladder over salivary glands; however, the clinical relevance of this finding has not been established."
http://www.mosbysdrugconsult.com/genrxfree/Top_200_1999/Drugs/E3309.htm

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Tolterodine Tartrate(Detrol), Why Prescribed, Health Square:"Detrol combats symptoms of overactive bladder, including frequent urination, urgency (increased need to urinate), and urge incontinence (inability to control urination). The drug works by blocking the nerve impulses that prompt the bladder to contract."
HealthSquare.com
68 East Main St
Somerville, NJ 08876
E-mail: comments@healthsquare.com
http://www.healthsquare.com/newrx/det1514.htm

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Tolterodine Tartrate, Range and Frequency, WholeHealthmd.com:"Adults: 2 mg, twice a day. Dose may be lowered by your doctor to 1 mg, twice a day, depending upon response to the medication. Adults with impaired liver function: no more than 1 mg, twice a day."
http://www.wholehealthmd.com/refshelf/drugs_view/0,1524,840,00.html

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Tolterodine Tartrate(Detrol), Approved For Bladder Control, March 26, 1998, Pharmcia & Upjohn:"An effective and well-tolerated new medication for the treatment of overactive bladder has been approved by the U.S. Food and Drug Administration. Detrol Tablets (tolterodine tartrate tablets) offers new hope to many of the estimated 17 million people in the U.S. coping with overactive bladder, a medical condition which can have profoundly negative effects on their quality of life. Detrol, a product of Pharmacia & Upjohn (NYSE: PNU) research, is the first new medication approved for a bladder control problem in the U.S. in more than 20 years."
http://tis-group.org/det_rel.html

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