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Metoprolol,Rxlist:"Hypertension: Extended release metoprolol succinate tablets are indicated for the treatment of hypertension. They may be used alone or in combination with other antihypertensive agents. Angina Pectoris: Extended release metoprolol succinate tablets are indicated in the long-term treatment of angina pectoris." http://www.rxlist.com/cgi/generic/metopxl_ids.htm ******************************************************
Metoprolol,P-I-E-N-O:"Metoprolol is a competitive, A-selective adrenergic antagonist, similar to atenolol. In contrast to pindolol, metoprolol does not have intrinsic sympathomimetic activity and does not exhibit membrane-stabilizing activities as both pindolol and propranolol possess. Metoprolol is more lipid soluble than atenolol, but less than propranolol and betaxolol, which affects its route of elimination and, theoretically, its potential for CNS side effects. Furthermore, metoprolol has the shortest plasma half-life of the cardioselective ś-blockers. Metoprolol was approved by the FDA in 1978." ******************************************************
Metoprolol,FP Notebook:"Indications: Chemical conversion of AV Node re-entry tachycardias. Paroxysmal Supraventricular Tachycardia (PSVT), Wolff-Parkinson-White Syndrome (WPW Syndrome), diagnosis in non-reentry tachycardias, Atrial flutter, Atrial Fibrillation,Ventricular Tachycardia." ******************************************************
Metoprolol,Health and Age:"Metoprolol blocks chemicals, such as adrenaline (epinephrine), and prevents them from increasing heart rate, blood pressure, and oxygen use. Metoprolol slows the body down a bit." ******************************************************
Metoprolol,genrx.com:"The mechanism of the antihypertensive effects of beta-blocking agents has not been elucidated. However, several possible mechanisms have been proposed: (1) competitive antagonism of catecholamines at peripheral (especially cardiac) adrenergic neuron sites, leading to decreased cardiac output; (2) a central effect leading to reduced sympathetic outflow to the periphery; and (3) suppression ." ******************************************************
Metoprolol,Healthwell:"Food increases the absorption of metoprolol.1 Metoprolol should be taken at the same time every day2 always with or always without food. Metoprolol may cause drowsiness, dizziness, lightheadedness, or blurred vision.3 Alcohol may intensify these effects and increase the risk of accidental injury. To prevent problems, people taking metoprolol should avoid alcohol." ******************************************************
Metoprolol,gnc.com:"Some beta-adrenergic blockers (called “nonselective” beta blockers) decrease the uptake of potassium from the blood into the cells,1 leading to excess potassium in the blood, a potentially dangerous condition known as hyperkalemia.2 People taking beta-blockers should therefore avoid taking potassium supplements, or eating large quantities of fruit (e.g., bananas), unless directed to do so by their doctor." ******************************************************
Metoprolol,aafp.org:"Angiotensin-converting enzyme (ACE) inhibitors are considered standard therapy in patients with left ventricular systolic dysfunction as the cause of their heart failure. However, chronic heart failure in general has a poor prognosis and, despite the benefits of ACE inhibitors, mortality and morbidity remain high in this patient population. Recent study results of the effects of beta1 blockade in patients with heart failure demonstrated a significant reduction in total mortality. " ******************************************************
Metoprolol,lysine.pharm:"Negative inotropic effect. This effect reduces the amount of work the heart does. Negative chronotropic effect. This effect reduces the amount of work the heart does. Antihypertensive. Due to effects on the heart and blood vessels. Initially, cardiac output is decreased with a lowering in blood pressure; eventually, cardiac output returns to normal but total peripheral resistance is decreased, presumably due to complex changes in cardiac function." ******************************************************
Metoprolol,Laurushealth.com:"Metoprolol is a beta-blocker drug used to reduce the symptoms of angina pectoris (chest pain), lower blood pressure in people with hypertension, and treat people after heart attacks. Metoprolol is available alone and in a combination product used to lower blood pressure."
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Last updated by Andrew
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