Nursing & Healthcare Directories on: The Nursefriendly
Immunosupressants, Organ Donation Rejection Agents,
Monoclonal Antibodies
Zenapax, Daclizumab

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Zenapax, What is this drug for? Centerwatch.com:"Hoffman-La Roche's new monoclonal antibody drug, Zenapax (daclizumab), has been approved to prevent rejection of kidney transplants. The drug uses the body's own immune system to prevent the acute rejection that can make kidney transplants fail."
Thomson CenterWatch
22 Thomson Place, 47F1
Boston, MA 02210-1212
Phone: (617) 856-5900 or Fax: (617) 856-5901
E-mail: visitor@centerwatch.com or cw.mailroom@centerwatch.com
http://www.centerwatch.com/patient/drugs/dru359.html

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Daclizumab Injection, How should I use this medicine? Drugdigest.com:"Daclizumab is for injection into a vein. It is given by a health-care professional in a hospital or clinic setting."
DrugDigest
Expresscripts.com
521 Alton Rd #208,
Miami Beach, FL 33140, US
E-mail: questions@express-scripts.com
http://www.drugdigest.org/DD/DVH/Uses/0,3915,6082|Daclizumab%2BInjection,00.html#howToTake

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Daclizumab, Warnings While Using This Medicine, Healthtouch.com:"Make sure your doctor knows if you are pregnant or breast feeding, or if you have high blood pressure or diabetes. This medicine may raise your blood sugar. Your doctor will need to check your blood at regular visits while you are using this medicine. Be sure to keep all appointments. You may be more likely to get infections while using this medicine. Tell your doctor if you have symptoms of an infection, such as fever or chills. Try to stay away from people with colds, flu, or other infections. Using this medicine may cause you to have a higher risk of getting cancer of the lymph system. Talk to your doctor if you have concerns about this risk."
Health Touch.com
Cardinal Health, Inc.
7000 Cardinal Place
Dublin, Ohio 43017 US
Phone: (614) 757-5014 or Fax: (614) 757-6014
http://www.healthtouch.com/bin/EContent_HT/dnoteShowLfts.asp?fname=04964&title=DACLIZUMAB+%28Injection%29+%28Injectable%29+&cid=HTDRUG

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Daclizumab, What is the most important information I should know about daclizumab? Healthyahoo.com:"Because it may cause serious side effects, daclizumab should only be prescribed by a doctor experienced in immunosuppressive therapy and the management of organ transplant patients. Discuss the risks and benefits of using this medication with your doctor. There may be an increased risk of infection with the use of daclizumab. Contact your doctor immediately if you develop signs of infection such as fever or chills; sore throat, coughing, congestion or other signs of infection; redness, pain, or swelling of a skin wound; or burning or difficult urination."
Health Yahoo.com
Yahoo! Inc.
701 First Avenue
Sunnyvale, CA, 94089 (US)
http://health.yahoo.com/drug/d04262a1#d04262a1-important

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Daclizumab, Pregnancy and Breastfeeding Considerations, Mayoclinic.com:"Pregnancy—Daclizumab crosses the placenta. However, daclizumab has not been studied in pregnant women. Breast-feeding—It is not known if daclizumab passes into breast milk. Breast-feeding is not recommended for patients receiving daclizumab."
Mayo Foundation for Medical Education and Research
200 1st St. S.W.
Rochester, MN 55905
E-mail: comments@mayoclinic.com
http://www.mayoclinic.com/invoke.cfm?objectid=9BAB433B-EE49-42F6-B210F006D55AD1B6#Before%20Using%20This%20Medicine

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Daclizumab Injection, DRUG INTERACTIONS, Medicinenet.com:"Tell your doctor of all nonprescription and prescription medication you may use, especially of: steroids (e.g., prednisone), other immunosuppressive drugs (e.g., cyclosporine, mycophenolate, azathioprine). Do not start or stop any medicine without doctor or pharmacist approval."
MedicineNet, Inc.
903 Calle Amanecer, Suite 300
San Clemente, CA 92673
Phone: (949) 940-6500 or Fax: (949) 940-1094
E-mail: smartservice@medicinenet.com
http://www.medicinenet.com/daclizumab-injection/page2.htm#DrugInteractions

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Daclizumab, Precautions While Using This Medicine, Medlineplus:"If you are continuing your course of therapy with daclizumab after you are discharged from the hospital, it is very important that your doctor check your progress at regular visits. Your doctor will want to do laboratory tests to make sure daclizumab is working properly.Dental—It is important to maintain good dental hygiene and see a dentist regularly for teeth cleaning.If you are a woman of childbearing age, you should use effective contraception while receiving this medicine."
National Library of Medicine
8600 Rockville Pike
Bethesda, Maryland 20894
Phone: (301) 496-6308 Fax: (301) 496-4450
E-mail: custserv@nlm.nih.gov
http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/203435.html#SXX20

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Zenapax, SIDE EFFECTS, Pharmacyhealth.com:"Nausea, vomiting, constipation or diarrhea may occur. If these effects persist or worsen, notify your doctor. Report promptly: stomach pain, headache, dizziness, chest pain, arm or leg swelling, trouble breathing, coughing, sore throat, fever, poor wound healing, bleeding, muscle pain, increased thirst or hunger, cloudiness or unusual change in amount of urine. Unlikely but report promptly: bloody urine or stools, weakness, leg cramps, increased sweating, mood/mental changes, arthritis pain, pain at the site of injection."
Yourlabtest.com
210 Fairfax Blvd.
Atlanta, GA 30319
Phone: (800) 209-1689.
E-mail: info@medpharmacy.com or info@pharmacyhealth.net
http://www.pharmacyhealth.net/d/zenapax-1780.htm

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Zenapax, OVERDOSE Symptoms, Rxlist.com:"There have not been any reports of overdoses with ZENAPAX. A maximum tolerated dose has not been determined in patients. A dose of 1.5 mg/kg has been administered to bone marrow transplant recipients without any associated adverse events."
RxList - The Internet Drug Index: Searchable Drug Database
RxList LLC
16092 San Dieguito Road
Rancho Sante Fe, CA 92067
Phone: (707) 747-0985 or Fax: (708) 575-8638
E-mail: info@rxlist.com
http://www.rxlist.com/cgi/generic3/zenapax_od.htm

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Zenapax, PRECAUTIONS with this Medicine, Webmd.com:"Before using this drug, tell your doctor your medical history, including: allergies (especially drug allergies), heart or lung disease, diabetes, high blood pressure, cancer, serious infection.Limit alcohol intake as it may enhance certain side effects of this medication.Since this drug may cause dizziness, use extreme caution if operating machinery or performing hazardous tasks (e.g., driving)."
Web MD
669 River Drive, Center 2
Elmwood Park, NJ 07407
Phone: (201) 703-3400 or Fax: (201) 703-3401
Sales Support: (1-877) GO-WEBMD
http://my.webmd.com/drugs/drug-5383-Zenapax+Intravenous.aspx?drugid=5383drugname=Zenapax+Intravenous#precautions

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Last updated by Andrew Lopez, RN on Monday, November 22, 2010


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