Aminophylline, What is aminophylline? Drugs.com:"Aminophylline is a bronchodilator. Aminophylline works in several ways: it relaxes muscles in your lungs and chest to allow more air in, decreases the sensitivity of your lungs to allergens and other substances that cause inflammation, and increases the contractions of your diaphragm to draw more air into the lungs. Aminophylline is used to treat the symptoms of asthma, bronchitis, and emphysema. Aminophylline may also be used for purposes other than those listed in this medication guide."
Hampstead Trust
ATTN: DRUGS.COM
c/o Network Solutions
P.O. Box 447
Herndon, VA 20172-0447
Phone: (570) 708-8780
E-mail: contact @ drugs.com
http://www.drugs.com/xq/cfm/pageid_0/htm_D00758A1.htm/type_mtm/tgid_36/bn_aminophylline/qx/index.htm

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Aminophylline, What drug(s) may interact with theophylline? Drugsdigest.com:"beta-blockers, often used for high blood pressure or heart problems.
•allopurinol
•barbiturate medicines for inducing sleep or treating seizures (convulsions)
•caffeine
•certain antibiotics given by injection
•diltiazem
•disulfiram
•ephedrine
•erythromycin
•fluvoxamine
•guarana
•influenza virus vaccine
•ketoconazole
•lansoprazole
•lithium
•medicines for colds and breathing difficulties
•medicine for stomach ulcers and other stomach problems
•methotrexate
•mexiletine
•prednisone
•rifampin
•seizure (convulsion) or epilepsy medicine
•St. John's wort
•tacrolimus
•thyroid hormones, such as levothyroxine and liothyronine
•verapamil
•zafirlukast
•zileuton

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines."
DrugDigest
Expresscripts.com
521 Alton Rd #208,
Miami Beach, FL 33140, US
E-mail: questions@express-scripts.com
http://www.drugdigest.org/DD/DVH/Uses/0,3915,7585|Aminophylline%2B%2528Theophylline%2529%2BInjection,00.html

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Aminophylline, Interactions with Herbs, Drugstore.com:"Pepper (Piper nigrum, Piper longum) Piperine is a chemical found in black peppers. A human study found that single doses of piperine could increase blood levels of theophylline.6 Hypothetically, such an elevation could lead to increased theophylline side effects or dose reductions without loss of drug efficacy. However, further study is required before such conclusions are made. People should not change the amount of theophylline taken without consulting their physician.

Tannin-containing herbs: Herbs high in tannins can impair the absorption of theophylline.7 High-tannin herbs include green tea, black tea, uva ursi (Arctostaphylos uva-ursi), black walnut (Juglans nigra), red raspberry (Rubus idaeus), oak (Quercus spp.), and witch hazel (Hamamelis virginiana).

St. John's wort (Hypericum perforatum): One case study of a 42-year old asthmatic woman reported that taking 300 mg per day of St. John's wort extract led to a significant decrease in blood levels of theophylline.8 Following discontinuation of St. John's wort, the patient's blood levels of theophylline returned to an acceptable therapeutic level. This may have occurred because certain chemicals found in St. John's wort activate liver enzymes that are involved in the elimination of some drugs.9 10 Until more is known, people taking theophylline should avoid St. John's wort."
Drugstore.com
407 Heron Drive
Swedesboro, NJ 08085-9810
Phone: (1-800) 378-4786
E-mail: aboutrx@drugstore.com
http://www.drugstore.com/templates/hnotes/default.asp?catid=40915&trx=SRCH-0-HN-AA&trxp2=40915#Dni-Herb

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Truphylline, Before Using This Medicine, Healthtouch.com:"In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For aminophylline, oxtriphylline, or theophylline, the following should be considered:

Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to aminophylline, ethylenediamine (contained in aminophylline), oxtriphylline, or theophylline.

Diet—Make certain your health care professional knows if you are on any special diet, such as a high-protein, low-carbohydrate or a low-protein, high-carbohydrate diet.

Pregnancy—Aminophylline, oxtriphylline, and theophylline are frequently used to treat asthma in pregnant women. Although there are no studies on birth defects in humans, problems have not been reported. Some studies in animals have shown that aminophylline, oxtriphylline, and theophylline can cause birth defects when given in doses many times the human dose.Because your ability to clear theophylline from your body may decrease later in pregnancy, your doctor may want to take blood samples during your pregnancy to measure the amount of medicine in the blood. This will help your doctor decide whether the dose of this medicine should be changed.Theophylline crosses the placenta. Use of aminophylline, oxtriphylline, or theophylline during pregnancy may cause unwanted effects such as fast heartbeat, irritability, jitteriness, or vomiting in the newborn infant if the amount of medicine in your blood is too high.

Breast-feeding—Theophylline passes into the breast milk and may cause irritability in nursing babies of mothers taking aminophylline, oxtriphylline, or theophylline.

Children—Very young children and newborn infants require a lower dose than older children. If the amount of theophylline in the blood is too high, side effects are more likely to occur. Your doctor may want to take blood samples to determine whether a dose change is needed.

Older adults—Patients older than 60 years of age are likely to require a lower dose than younger adults. If the amount of theophylline is too high, side effects are more likely to occur. Your doctor may want to take blood samples to determine whether a dose change is needed.

Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking aminophylline, oxtriphylline, or theophylline, it is especially important that your health care professional know if you are taking any of the following: Beta-adrenergic blocking agents including those used in the eyes (acebutolol [e.g., Sectral], atenolol [e.g., Tenormin], betaxolol [e.g., Betoptic, Kerlone], bisoprolol [e.g., Zebeta], carteolol [e.g., Cartrol], labetalol [e.g., Normodyne], levobunolol [e.g., Betagan], metipranolol [e.g., OptiPranolol], metoprolol [e.g., Lopressor], nadolol [e.g., Corgard], oxprenolol [e.g., Trasicor], penbutolol [e.g., Levatol], pindolol [e.g., Visken], propranolol [e.g., Inderal], sotalol [e.g., Sotacor], timolol [e.g., Blocadren, Timoptic])—These medicines may prevent aminophylline, oxtriphylline, or theophylline from working properly
Cimetidine (e.g., Tagamet) or
Ciprofloxacin (e.g., Cipro) or
Clarithromycin (e.g., Biaxin) or
Enoxacin (e.g., Penetrex) or
Erythromycin (e.g., E-Mycin) or
Fluvoxamine (e.g., Luvox) or
Mexiletine (e.g., Mexitil) or
Pentoxifylline (e.g., Trental) or
Propranolol (e.g., Inderal) or
Tacrine (e.g., Cognex) or
Thiabendazole or
Ticlopidine (e.g., Ticlid) or
Troleandomycin (e.g., TAO)—These medicines may increase the effects of aminophylline, oxtriphylline, or theophylline
Moricizine (e.g., Ethmozine) or
Phenytoin (e.g., Dilantin) or
Rifampin (e.g., Rifadin)—These medicines may decrease the effects of aminophylline, oxtriphylline, or theophylline
Smoking tobacco or marijuana—Starting or stopping smoking may change the effectiveness of these medicines.

Other medical problems—The presence of other medical problems may affect the use of aminophylline, oxtriphylline, or theophylline. Make sure you tell your doctor if you have any other medical problems, especially: Convulsions (seizures)—Aminophylline, oxtriphylline, or theophylline may make this condition worse: Heart failure or Liver disease or Underactive thyroid—The effects of aminophylline, oxtriphylline, or theophylline may be increased."
Health Touch.com
Cardinal Health, Inc.
7000 Cardinal Place
Dublin, Ohio 43017 US
Phone: (614) 757-5014 or Fax: (614) 757-6014
http://www.healthtouch.com/bin/EContent_HT/drugShowLfts.asp?fname=usp0001.htm&title=Truphylline+%2C+Aminophylline&cid=HTDRUG

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Aminophylline, What is the most important information I should know about aminophylline? Healthyahoo.com:"Do not crush or chew any extended-release formulation of aminophylline. Swallow the medication whole. It is specially formulated to release slowly in your body. If you do not know whether your medication is an extended-release formulation, ask your pharmacist. Call your doctor right away if you experience nausea, vomiting, insomnia, restlessness, seizures, increased heart rate, or a headache. These could be signs of too much aminophylline in your blood. Do not start or stop smoking without your doctor's knowledge. Smoking may affect your dosage. Do not take more of this medication than is prescribed without consulting your doctor. Seek medical attention if you are having increasing difficulty breathing."
Health Yahoo.com
Yahoo! Inc.
(DOM-272993)
701 First Avenue
Sunnyvale, CA, 94089 US
http://health.yahoo.com/drug/d00758a1#d00758a1-important

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Theophylline, Dosing, Mayoclinic.com:Dosing: "When you are taking aminophylline, oxtriphylline, or theophylline, it is very important that you get the exact amount of medicine that you need. The dose of these medicines will be different for different patients. Your doctor will determine the proper dose of these medicines for you. Follow your doctor's orders or the directions on the label. After you begin taking aminophylline, oxtriphylline, or theophylline, it is very important that your doctor check the level of medicine in your blood at regular intervals to find out if your dose needs to be changed. Do not change your dose of aminophylline, oxtriphylline, or theophylline unless your doctor tells you to do so .The number of capsules or tablets or teaspoonfuls of solution or syrup that you take depends on the strength of the medicine. Also, the number of doses you take each day and the time between doses depend on whether you are taking a short-acting or long-acting form of aminophylline, oxtriphylline, or theophylline."
Mayo Foundation for Medical Education and Research
200 1st St. S.W.
Rochester, MN 55905
E-mail: comments@mayoclinic.com
http://www.mayoclinic.com/invoke.cfm?retryCount=1&objectid=509CC181-038B-41F6-A706840CB80622DC

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Aminophylline, How is this medicine supplied and How should this medicine be used?, Medlineplus.com:"Aminophylline comes as a tablet and syrup to take by mouth and a suppository to insert rectally. It usually is taken every 6, 8, or 12 hours. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take aminophylline exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Take the tablets or oral liquid with a full glass of water on an empty stomach, at least 1 hour before or 2 hours after a meal. Do not chew or crush the long-acting tablets; swallow them whole.Aminophylline controls symptoms of asthma and other lung diseases but does not cure them. Continue to take aminophylline even if you feel well. Do not stop taking aminophylline without talking to your doctor.

To insert a rectal suppository, follow these steps:
Remove the wrapper.
Dip the tip of the suppository in water.
Lie down on your left side and raise your right knee to your chest. (A left-handed person should lie on the right side and raise the left knee.)
Using your finger, insert the suppository into the rectum, about 1/2-1 inch in infants and children and 1 inch in adults. Hold it in place for a few moments.
Stand up after about 15 minutes. Wash your hands thoroughly and resume your normal activities."
National Library of Medicine
8600 Rockville Pike
Bethesda, Maryland 20894
Phone: (301) 496-6308 Fax: (301) 496-4450
E-mail: custserv@nlm.nih.gov
http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601015.html#how

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Aminophylline, What happens if I miss a dose? Peacehealth.org:"Take the missed dose as soon as you remember. However, if it is almost time for your next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication."
Healthwise, Incorporated
P.O. Box 1989
2601 N. Bogus Basin Road
Boise, Idaho 83701
Phone: (1-800) 706-9646
http://www.peacehealth.org/kbase/multum/d00758a1.htm

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Aminophylline, Storage, Rxlist.com:"Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture. Throw away any medication that is outdated or no longer needed."
RxList - The Internet Drug Index: Searchable drug database.
RxList LLC
16092 San Dieguito Road
Rancho Sante Fe, CA 92067
Phone: (707) 747-0985 or Fax: (708) 575-8638
E-mail: info@rxlist.com
http://www.rxlist.com/cgi/pharmclips2.cgi?keyword=%20aminophylline#storage

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Aminophylline, What special dietary instructions should I follow?, Safemedication.com:"Drinking or eating foods high in caffeine, like coffee, tea, cocoa, and chocolate, may increase the side effects caused by aminophylline. Avoid large amounts of these substances while you are taking aminophylline."
American Society of Health-System Pharmacists
7272 Wisconsin Avenue
Bethesda, MD 20814
Phone: (301) 657-3000 x1218
http://www.safemedication.com/displaydrug.cfm?id=601015

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