Nursing & Healthcare Directories on: The Nursefriendly
Skeletal Muscle Relaxants, Centrally Acting,
Flexeril, Cyclobenzaprine Hydrochloride

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Cyclobenzaprine, Indications, RXlist:"Cyclobenzaprine HCl is indicated as an adjunct to rest and physical therapy for relief of muscle spasm associated with acute, painful musculoskeletal conditions.Improvement is manifested by relief of muscle spasm and its associated signs and symptoms, namely, pain, tenderness, limitation of motion, and restriction in activities of daily living."
http://www.rxlist.com/cgi/generic/cyclobnz_ids.htm

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Cyclobenzaprine, Side Effects, MedicineNet.com:"Among the most common side effects of cyclobenzaprine are drowsiness (which occurs in between 1 in 6 and 1 in 3 persons), dry mouth (between 1 in 14 and 1 in 4), and dizziness (between 1 in 30 and 1 in 9). Other reported side effects, for which the incidence is less than 1 in 30, include nausea, tiredness, constipation , blurred vision, unpleasant taste, nervousness, confusion, and abdominal pain or discomfort."
http://www.focusonmedications.com/script/main/Art.asp?li=MNI&ArticleKey=939

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Cyclobenzaprine, Description, MEDLINEplus Drug Information:"Cyclobenzaprine (sye-kloe-BEN-za-preen) is used to help relax certain muscles in your body. It helps relieve the pain, stiffness, and discomfort caused by strains, sprains, or injuries to your muscles. However, this medicine does not take the place of rest, exercise or physical therapy, or other treatment that your doctor may recommend for your medical problem. Cyclobenzaprine acts on the central nervous system (CNS) to produce its muscle relaxant effects. Its actions on the CNS may also cause some of this medicine's side effects."
U.S. National Library of Medicine
8600 Rockville Pike, Bethesda, MD 20894
custserv@nlm.nih.gov
http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682514.html

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Cyclobenzaprine(Flexeril), Muscle Relaxants, Spine-health.com:"Cyclobenzaprine (Flexeril). This medication can be used on a longer-term basis and actually has a chemical structure related to some antidepressant medications, although it is not an antidepressant. Usually it is prescribed as 10mg every six hours as needed to relieve low back pain associated with muscle spasm, or it can also be prescribed as 10mg at night as needed to help with difficulty sleeping. Flexeril can impair mental and physical function, and may lead to urinary retention in males with large prostates."
http://www.spine-health.com/topics/conserv/overview/med/med04.html

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Cyclobenzaprine(Flexeril), Health Library, LaurusHealth.com:"Cyclobenzaprine may cause dizziness, drowsiness, or blurred vision. 1 Alcohol may intensify these effects and increase the risk of accidental injury. To prevent problems, people taking cyclobenzaprine should avoid alcohol."
http://www.laurushealth.com/Library/HealthGuide/CAM/topic.asp?hwid=hn-drug-cyclobenzaprine

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Cyclobenzaprine, Clinical Studies, Mosby's Drug Consult:"Controlled clinical studies show that cyclobenzaprine HCl significantly improves the signs and symptoms of skeletal muscle spasm as compared with placebo. The clinical responses include improvement in muscle spasm as determined by palpation, reduction in local pain and tenderness, increased range of motion, and less restriction in activities of daily living. When daily observations were made, clinical improvement was observed as early as the first day of therapy."
http://www.genrx.com/genrxfree/Top_200_1999/Drugs/E0926.htm

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Cyclobenzaprine(Flexeril), Most important fact about this drug, Getting Well Network:"Flexeril is not a substitute for the physical therapy, rest, or exercise that your doctor orders for proper healing. Although Flexeril relieves the pain of strains and sprains, it is not useful for other types of pain."
http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/fle1179.shtml

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Cyclobenzaprine, Who is this for, Drug Digest:"Cyclobenzaprine, a muscle relaxant, is used with rest, physical therapy, and other measures to relax muscles and relieve pain and discomfort caused by strains, sprains, and other muscle injuries. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information."
http://www.drugdigest.org/DD/DVH/Uses/0,3915,176|Flexeril,00.html

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Last updated by Andrew Lopez, RN on Monday, November 22, 2010


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