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Hydrocortisone Sodium Phosphate, Mechanism
of action/Effect, Drugs.com:"Corticosteroids diffuse across cell membranes
and complex with specific cytoplasmic receptors.
These complexes then enter the cell nucleus,
bind to DNA, and stimulate transcription
of messenger RNA (mRNA) and subsequent protein
synthesis of various enzymes thought to be
ultimately responsible for two categories
of effects of systemic corticosteroids. However,
these agents may suppress transcription of
mRNA in some cells (e.g., lymphocytes)."
Hampstead Trust
ATTN: DRUGS.COM
c/o Network Solutions
P.O. Box 447
Herndon, VA 20172-0447
Phone: (570) 708-8780
E-mail: contact @ drugs.com
http://www.drugs.com/MMX/Hydrocortisone_Sodium_Phosphate.html
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Hydrocortone Phosphate, What is this drug for? Drugdigest.org:"HYDROCORTISONE (Hydrocortone Acetate®, Hydrocortone Phosphate®, A-HydroCort®, Solu-Cortef®) is a corticosteroid. It helps to reduce swelling, redness, itching, and allergic reactions. Hydrocortisone is similar to natural steroid hormone produced by the adrenal gland. Hydrocortisone treats severe allergies, skin problems, asthma, arthritis, or many other conditions."DrugDigest
Expresscripts.com
521 Alton Rd #208,
Miami Beach, FL 33140, US
E-mail: questions@express-scripts.com
http://www.drugdigest.org/DD/DVH/Uses/0,3915,326%7CHydrocortone+Phosphate,00.html#uses
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Hydrocortone Phosphate, Proper Storage, Healthtouch.com:"To store this medicine:Keep out of the reach of children. Store away from heat and direct light. Do not store capsules or tablets in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down. Keep the liquid dosage forms of this medicine from freezing."Health Touch.com
Cardinal Health, Inc.
7000 Cardinal Place
Dublin, Ohio 43017 US
Phone: (614) 757-5014 or Fax: (614) 757-6014
http://www.healthtouch.com/bin/EContent_HT/drugShowLfts.asp?fname=usp0364.htm&title=Hydrocortone+Phosphate+%2C+Hydrocortisone&cid=HT
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Corticosteroids, Use in Children, Mayoclinic.com:"Corticosteroids may cause infections such as chickenpox or measles to be more serious in children who catch them. These medicines can also slow or stop growth in children and in growing teenagers, especially when they are used for a long time. Before this medicine is given to children or teenagers, you should discuss its use with your child's doctor and then carefully follow the doctor's instructions."Mayo Foundation for Medical Education and Research
200 1st St. S.W.
Rochester, MN 55905
E-mail: comments@mayoclinic.com
http://www.mayoclinic.com/invoke.cfm?objectid=BF779C0C-E238-4235-A3D4F14F4B11D954#Before%20Using%20This%20Medicine
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Hydrocortone, Important things you should know about hydrocortisone, Medicationadvisor.com: "Carry some type of medical identification that will let others know you are taking hydrocortisone in the case of an emergency. Do not stop taking hydrocortisone suddenly if you have been taking it for a few weeks. You may need a gradual reduction in dosage before you stop taking this medication. Take oral hydrocortisone with food or milk to lessen stomach upset."Applied Informatics, LLC
5312 Pawnee Lane
Fairway KS 66205 USA
Phone: (913) 671-1885
E-mail: info@medicationadvisor.com
http://www.medicationadvisor.com/side_effects/Hydrocortone.htm
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Hydrocortone Acetate, DRUG INTERACTIONS, Medicinenet.com:"Tell your doctor of all prescription and nonprescription medication you may use, especially: phenytoin, barbiturates (e.g., phenobarbital, primidone), rifamycin antibiotics (e.g., rifampin, rifabutin), macrolide antibiotics (e.g., clarithromycin, erythromycin), high-dose aspirin or aspirin-like drugs (e.g., salsalate, magnesium salicylate), neuromuscular blocking drugs (e.g., pancuronium, vecuronium), "water pills" (e.g., potassium-sparing diuretics such as spironolactone or triamterene), antifungal drugs (e.g., itraconazole, ketoconazole), estrogen-containing drugs (e.g., birth control pills, estradiol), "blood thinners" (e.g., warfarin)."MedicineNet, Inc.
903 Calle Amanecer, Suite 300
San Clemente, CA 92673
Phone: (949) 940-6500 or Fax: (949) 940-1094
E-mail: smartservice@medicinenet.com
http://www.medicinenet.com/hydrocortisone_acetate-injection/page3.htm#DrugInteractions
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Corticosteroids, Proper Use of This Medicine, Medlineplus:"Use this medicine only as directed by your doctor. Do not use more or less of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may increase the chance of side effects."National Library of Medicine
8600 Rockville Pike
Bethesda, Maryland 20894
Phone: (301) 496-6308 Fax: (301) 496-4450
E-mail: custserv@nlm.nih.gov
http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202018.html#SXX15
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Hydrocortisone, Possible Adverse Reactions or Side Effects, MDadvice.com:"Life-threatening—Hives, rash, intense Seek emergency itching, faintness treatment immediately. soon after a dose (anaphylaxis).Common—Acne, poor wound healing, thirst, indigestion, nausea, vomiting.Infrequent—Black, bloody or tarry stools. Blurred vision; halos around lights; sore throat; fever; muscle cramps; swollen legs, feet. Mood change, insomnia, fatigue, restlessness, frequent urination, weight gain, round face, weakness, irregular menstrual periods."MDAdvice.com
151 West Passaic Street
Rochelle Park, NJ 07662
Phone: (201) 767-4273
E-mail: feedback@mdadvice.com
http://www.mdadvice.com/library/drug/drug215.html
****************************************************
Corticosteroids, Pregnancy and Breastfeeding Considerations, Medicineonline.com:"Pregnancy—Studies on birth defects with corticosteroids have not been done in humans. However, studies in animals have shown that corticosteroids cause birth defects. Breast-feeding—Corticosteroids pass into breast milk and may cause problems with growth or other unwanted effects in nursing babies. Depending on the amount of medicine you are taking every day, it may be necessary for you to take another medicine or to stop breast-feeding during treatment."Medicine Online Inc.
18800 Delaware Street, Suite 650
Huntington Beach, CA 92648-6017
Toll-free phone: (1-888) 666-5638
Phone: (1-714) 848-0444 or Fax: (1-714) 841-6504
E-mail: info@mol.net
http://www.medicineonline.com/druginfo/info2/A-hydroCort/Corticosteroids_Glucocorticoid_Effects_Systemic/
****************************************************
Hydrocortone Acetate Injection, Precautions when using in Infants, Webmd.com:"A preservative (benzyl alcohol) which may be found in this product or in the liquid used to mix this product (diluent) can infrequently cause serious problems (sometimes death), if given in large amounts (more than 100 mg/kg daily) to an infant during the first months of life (neonatal period). The risk is also greater with low birth weight infants. Symptoms include sudden gasping, low blood pressure, or a very slow heartbeat. Report these symptoms to the doctor immediately should they occur. If possible, a preservative-free product should be used when treating neonates."Web MD
669 River Drive, Center 2
Elmwood Park, NJ 07407
Phone: (201) 703-3400 or Fax: (201) 703-3401
Sales Support: (1-877) GO-WEBMD
E-mail Contact Form: http://www.webmd.com/about-webmd-policies/about-contact-us
http://my.webmd.com/drugs/drug-52987-Hydrocortone+Acetate+Injection.aspx?drugid=52987&drugname=Hydrocortone+Acetate+Injection#precautions
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Last updated by Andrew Lopez, RN on Thursday, January 28, 2010